Verorab (Inactivated Purified Rabies Vaccine) Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info Full Prescribing Info Contents Description Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Inactivated purified rabies vaccine prepared on vero cells

Indications/Uses

Pre- & post-exposure immunization against rabies.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Dosage/Direction for Use

Pre-exposure vaccination 3 doses of 0.5 mL IM inj on D0, D7, D21 or D28, followed by booster dose after 1 yr & subsequent booster dose every 5 yr. Post-exposure vaccination Non-immunized patients Essen regimen: 5 doses of 0.5 mL IM inj on D0, D3, D7, D14 & D28. Zagreb regimen (schedule 2-1-1): 4 doses of 0.5 mL IM inj on D0, D7 & D21. 1 inj in each of the 2 deltoids or anterolateral thigh sites. Updated Thai Red Cross regimen: 2 doses each of 0.1 mL intradermal inj at different sites on D0, D3, D7 & D28. 1 wk, 4-site regimen: 4 doses each of 0.1 mL intradermal inj at 4 distinct sites on D0, D3 & D7. Fully immunized patients 1 dose of 0.5 mL IM inj or 0.1 mL intradermal inj on D0 & D3.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Overdosage

View Verorab (Inactivated Purified Rabies Vaccine) overdosage for action to be taken in the event of an overdose.

Contraindications

Pre-exposure: Hypersensitivity to rabies virus, polymyxin B, streptomycin, neomycin or to any antibiotic of the same group, previous administration or to any vaccine containing the same components. Severe febrile infection, acute disease, progressive chronic disease. Post-exposure: No contraindication to curative vaccine. Pregnancy.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Special Precautions

Known allergy to neomycin, polymyxin B, streptomycin or any antibiotic of the same group. May not protect 100% of people vaccinated. Not to be inj intravascularly or into gluteal region. Conduct serological test on persons subject to continuous exposure (every 6 mth) & may be conducted every 2-3 yr after the booster dose after 1 & 5 yr in persons subject to discontinuous exposure according to the assessed exposure risk; may be conducted 2-4 wk following the vaccination for immune deficient subjects. Thrombocytopenia or coagulation disorders. Potential risk of apnoea; monitor resp for 48-72 hr after primary immunization to very premature infants (≤28 wk of gestation) & particularly for those w/ previous history of resp immaturity; do not w/hold or delay vaccination. Anxiety-related reactions eg, vasovagal reactions (syncope), hyperventilation or stress-related reactions. May temporarily affect ability to drive or use machines. Pregnancy & lactation.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Use In Pregnancy & Lactation

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Adverse Reactions

Adenopathy/lymphadenopathy; myalgia; inj site pain, fever, malaise. Cutaneous allergic reactions eg, rash, pruritus, oedema; headache, dizziness, somnolence; abdominal pain, nausea; arthralgia, shivering; inj site erythema, pruritus, swelling, haematoma, induration, asthenia, flu-like syndrome. Anaphylactic reactions, serum sickness-like reactions, encephalopathy, convulsions; sudden hearing loss; apnoea in very premature infants; vomiting.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Drug Interactions

May interfere Ab production w/ corticosteroids & immunosuppressor treatments. Perform a neutralizing Ab assay 2-4 wk after last inj. Rabies Ig & vaccine must never be combined in the same syringe or administered at the same site. Administer vaccine contralaterally to the Ig administration sites.

Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Verorab (Inactivated Purified Rabies Vaccine) detailed prescribing information

Storage

View Verorab (Inactivated Purified Rabies Vaccine) storage conditions for details to ensure optimal shelf-life.

Description

View Verorab (Inactivated Purified Rabies Vaccine) description for details of the chemical structure and excipients (inactive components).

MIMS Class

Vaccines, Antisera & Immunologicals

ATC Classification

J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.

Regulatory Classification

Presentation/Packing

Form

Verorab (Inacrivated Purified Rabies Vaccine) vaccine (inj) 0.5 mL

Packing/Price

(vial) 10 × 1's; (vial) 1's (Rp347,698/boks)

Verorab (Inactivated Purified Rabies Vaccine)

rabies vaccine

Manufacturer:

Kalventis Sinergi Farma